Publications

2019

Roder AE, Vazquez C, Horner SM. The acidic domain of the hepatitis C virus NS4A protein is required for viral assembly and envelopment through interactions with the viral E1 glycoprotein. PLoS Pathog. 2019;15(2):e1007163. PMID: 30730994.

Roder AE, Horner SM. Measuring Hepatitis C Virus Envelopment by Using a Proteinase K Protection Assay. Methods Mol Biol. 2019;1911:209-17. PMID: 30593628.

2018

Dethoff EA*, Boerneke MA*, Gokhale NS, Muhire BM, Martin DP, Sacco MT, McFadden MJ, Weinstein JA, Messer WB**, Horner SM**, Weeks KM**. Pervasive tertiary structure in the dengue virus RNA genome. Proc Natl Acad Sci U S A. 2018;115(45):11513-8. PMID: 30341219. *Equal contribution **Co-corresponding

Imam H, Khan M, Gokhale NS, McIntyre ABR, Kim GW, Jang JY, Kim SJ, Mason CE, Horner SM, Siddiqui A. N6-methyladenosine modification of hepatitis B virus RNA differentially regulates the viral life cycle. Proc Natl Acad Sci U S A. 2018. doi: 10.1073/pnas.1808319115. PMID: 30104368.

Wang L, Pittman KJ, Barker JR, Salinas RE, Stanaway IB, Williams GD, Carroll RJ, Balmat T, Ingham A, Gopalakrishnan AM, Gibbs KD, Antonia AL, e MN, Heitman J, Lee SC, Jarvik GP, Denny JC, Horner SM, DeLong MR, Valdivia RH, Crosslin DR, Ko DC. An Atlas of Genetic Variation Linking Pathogen-Induced Cellular Traits to Human Disease. Cell Host Microbe. 2018;24(2):308-23 e6. PMID: 30092202

Liu B, Merriman DK, Choi SH, Schumacher MA, Plangger R, Kreutz C, Horner SM, Meyer KD, Al-Hashimi HM. A potentially abundant junctional RNA motif stabilized by m(6)A and Mg(2). Nat Commun. 2018;9(1):2761. doi: 10.1038/s41467-018-05243-z. PMID: 30018356

McFadden MJ, Mitchell-Dick A, Vazquez C, Roder AE, Labagnara KF, McMahon JJ, Silver DL, Horner SM. (2018) A Fluorescent Cell-Based System for Imaging Zika Virus Infection in Real-Time. Viruses. 2018;10(2). doi: 10.3390/v10020095. PMID: 29495257

2017

Gokhale NS, Horner SM. 2017. RNA modifications go viral. PLoS Pathog 13:e1006188. PMCID: PMC5344520

Vazquez C, Beachboard DC, Horner SM. 2017. Methods to Visualize MAVS Subcellular Localization. Methods Mol Biol 1656:131-142. PMID: 28808966

Gokhale NS, Horner SM. Knotty Zika virus blocks exonuclease to produce subgenomic flaviviral RNAs. Cell Host Microbe. 2017. 21(1). PMID: 28081439

McFadden MJ, Gokhale NS, Horner SM. Protect this house: cytosolic sensing of viruses. Curr Opin Virology. 2017; 22:36-43. PMID: 27951430.

2016

Gokhale NS, McIntyre ABR, McFadden MJ, Roder AE, Kennedy EM, Gandara JA, HopcraftSE, Quicke KM, Vazquez  C, Willer J, Ilkayeva OR, Law BA, Holley CL, Garcia-Blanco MA,Evans MJ, Suthar MS, Bradrick SS, Mason CE*, Horner SM*. N6-methyladenosine in Flaviviridae viral RNA genomes regulates infectionCell Host Microbe. 2016. 20(5):654-665. PMID: 27773535. *Co-corresponding. Featured on the Cover.

Jarret A, McFarland AP*, Horner SM*, Kell A, Schwerk J, Hong M, Badil S, Joslyn RC, Baker DP, Carrington M, Hagedorn CH, Gale M, Jr., Savan R. Hepatitis C virus-induced microRNAs dampen interferon mediated antiviral signaling. Nat Med. 2016. 22: 1475-1481. PMID: 27841874. *Equal contribution

Beachboard, DC, Horner SM. Innate immune evasion strategies of DNA and RNA viruses. Curr Opin Microbiol. 2016; 32:113-119. PMCID: 4983539  

Kennedy EM, Bogerd HP, Kornepati AVR, Kang B, Ghoshal D, Marshall JB, Poling BC, Tsai G, Gokhale N, Horner SM, Cullen BR. Post-transcriptional m6A editing of HIV-1 mRNAs enhances viral gene expression. Cell Host Microbe. 2016; 19(5): 675-85. PMCID: 4867121

2015

Aligeti M*, Roder A*, Horner SM. Cooperation between the Hepatitis C Virus p7 and NS5B Proteins Enhances Virion Infectivity. J Virol. 2015;89(22):11523-33. PMCID: 4645646. *Equal Contribution

Vazquez C, Horner SM. MAVS Coordination of Antiviral Innate Immunity. J Virol. 2015;89(14):6974-7. PMCID: 4473567.

Horner SM*, Naggie S*. Successes and Challenges on the Road to Cure Hepatitis C. PLoS Pathog. 2015;11(6):e1004854. PMCID: 4472668. *Corresponding Author

Horner SM*, Wilkins C, Badil S, Iskarpatyoti J, Gale M, Jr. Proteomic Analysis of Mitochondrial-Associated ER Membranes (MAM) during RNA Virus Infection Reveals Dynamic Changes in Protein and Organelle Trafficking. PLoS One. 2015;10(3):e0117963. PMCID: 4348417. *Corresponding Author

Horner SM. Insights into antiviral innate immunity revealed by studying hepatitis C virus. Cytokine. 2015;74(2):190-7. PMCID: 4475425.

2014

Gokhale NS, Vazquez C, Horner SM. Hepatitis C virus: Strategies to evade antiviral responses. Future Virol. 2014;9(12):1061-75. PMCID: 4430848.

Horner SM. Defining the spatial relationship between hepatitis C virus infection and interferon stimulated gene induction in the human liver. Hepatology. 2014 APR: doi: 10.1002/hep.26960. PMID: 24375835.

Horner SM. Activation and evasion of antiviral innate immunity by hepatitis C virus. J Mol Biol. 2014 MAR: 426(6):1198-209. PMID: 24184198.

McFarland AP, Horner SM, Jarret A, Joslyn RC, Bindewald E, Shapiro BA, Delker DA, Hagedorn C, Carrington M, Gale M, Jr., Savan R. IFNL3 (IL28B) favorable genotype escapes HCV-induced microRNAs and mRNA decay. Nat Immunol. 2014 Jan;15(1):72-9. PMID: 24241692.

2013

Horner SM, Gale, M, Jr. Regulation of hepatic innate immunity by hepatitis C virus. Nat Med. 2013; 19(7): 879-88. PMID: 23836238.

2012

Horner SM, Gale M, Jr. Regulation of innate immunity and interferon defenses by hepatitis C virus. In Chronic Hepatitis B and C. Edited by C. Shih. World Scientific Publishing Co., Singapore, 2012. pp. 245-270.

Liu HM, Loo YM, Horner SM, Zornetzer GA, Katze MG, Gale M, Jr. The Mitochondrial Targeting Chaperone 14-3-3epsilon Regulates a RIG-I Translocon that Mediates Membrane Association and Innate Antiviral Immunity. Cell Host Microbe. 2012;11(5):528-37. PMID: 22607805.

Patel MR, Loo YM, Horner SM, Gale M, Jr., Malik HS. Convergent evolution of escape from hepaciviral antagonism in primates. PLoS Biol. 2012;10(3):e1001282. PMCID: 3302847.

Horner SM, Park HS, Gale M, Jr. Control of innate immune signaling and membrane targeting by the Hepatitis C virus NS3/4A protease are governed by the NS3 helix alpha0. J Virol. 2012;86(6):3112-20. PMCID: 22238314.

2011

Horner SM, Liu HM, Park HS, Briley J, Gale M, Jr. Mitochondrial-associated endoplasmic reticulum membranes (MAM) form innate immune synapses and are targeted by hepatitis C virus. Proc Natl Acad Sci U S A. 2011. PMID: 21844353.

Pre-2011

Horner SM, Gale M, Jr. Intracellular innate immune cascades and interferon defenses that control hepatitis C virus. J Interferon Cytokine Res. 2009;29(9):489-98.PMID: 19708811.

DiMaio, D, Johung, K, Goodwin, EC, Horner, SM and Yates, KE. Senescence induced by repression of human papillomavirus oncogenes in cervical cancer cells. In Beyond Apoptosis: Cellular Outcomes of Cancer Therapy. Edited by IB Roninson, JM Brown, and DE Bredesen. Informa Healthcare, New York, 2008. pp209-222.

Horner SM, DiMaio D. The DNA binding domain of a papillomavirus E2 protein programs a chimeric nuclease to cleave integrated human papillomavirus DNA in HeLa cervical carcinoma cells. J Virol. 2007;81(12):6254-64. PMCID: 17392356.

Horner SM, DeFilippis RA, Manuelidis L, DiMaio D. Repression of the human papillomavirus E6 gene initiates p53-dependent, telomerase-independent senescence and apoptosis in HeLa cervical carcinoma cells. J Virol. 2004;78(8):4063-73. PMCID: 15047823.

Sherer NM, Lehmann MJ, Jimenez-Soto LF, Ingmundson A, Horner SM, Cicchetti G, et al. Visualization of retroviral replication in living cells reveals budding into multivesicular bodies. Traffic. 2003;4(11):785-801. PMID: 14617360.

http://www.ncbi.nlm.nih.gov/sites/myncbi/stacy.horner.1/bibliography/41117578/public/?sort=date&direction=descending